Zolpidemdosage

Take only if 4 hours of bedtime remain before the planned time of waking Zolpidem tartrate sublingual tablets should be placed under the tongue and allowed to disintegrate completely before swallowing. The tablet should not be swallowed whole. The effect of zolpidem tartrate sublingual tablets may be slowed if taken with or immediately after a meal Recommended dose is 1.75 mg for women and 3.5 mg for men, taken only once per night if needed Lower doses of CNS depressants may be necessary when taken concomitantly with zolpidem tartrate sublingual tablets Co-administration with CNS depressants: Recommended dose is 1.75 mg for men and women Geriatric patients and patients with hepatic impairment: Recommended dose is 1.75 mg for men and women

2.1 Important

Administration Instructions Zolpidem tartrate sublingual tablets are to be taken in bed when a patient wakes in the middle of the night and has difficulty returning to sleep. Zolpidem tartrate sublingual tablets should only be taken if the patient has at least 4 hours of bedtime remaining before the planned time of waking. Zolpidem tartrate sublingual tablets should be placed under the tongue and allowed to disintegrate completely before swallowing. The tablet should not be swallowed whole. For optimal effect, Zolpidem tartrate sublingual tablets should not be administered with or immediately after a meal. The tablet should be removed from the pouch just prior to dosing.

2.2 Basic Dosing

Information The recommended and maximum dose of zolpidem tartrate sublingual tablets are 1.75 mg for women and 3.5 mg for men, taken only once per night as needed if a middle-of-the-night awakening is followed by difficulty returning to sleep. The recommended doses for women and men are different because women clear zolpidem from the body at a lower rate than men.

2.3 Use with CNS

Depressants The recommended zolpidem tartrate sublingual tablets dose for men and women who are taking concomitant CNS depressants is 1.75 mg. Dose adjustment of concomitant CNS depressants may be necessary when co-administered with zolpidem tartrate sublingual tablets because of potentially additive effects. The use of zolpidem tartrate sublingual tablets with other sedative-hypnotics (including other zolpidem products) at bedtime or the middle of the night is not recommended.

2.4 Use in Geriatric

Patients Geriatric patients may be especially sensitive to the effects of zolpidem. The recommended dose of zolpidem tartrate sublingual tablets in men and women over 65 years old is 1.75 mg, taken only once per night if needed.

2.5 Use in Patients with

Hepatic Impairment The recommended dose of zolpidem tartrate sublingual tablets in patients with hepatic impairment is 1.75 mg, taken only once per night if needed.

2.1 Important

Administration Instructions Zolpidem tartrate sublingual tablets are to be taken in bed when a patient wakes in the middle of the night and has difficulty returning to sleep. Zolpidem tartrate sublingual tablets should only be taken if the patient has at least 4 hours of bedtime remaining before the planned time of waking. Zolpidem tartrate sublingual tablets should be placed under the tongue and allowed to disintegrate completely before swallowing. The tablet should not be swallowed whole. For optimal effect, Zolpidem tartrate sublingual tablets should not be administered with or immediately after a meal. The tablet should be removed from the pouch just prior to dosing.

2.2 Basic Dosing

Information The recommended and maximum dose of zolpidem tartrate sublingual tablets are 1.75 mg for women and 3.5 mg for men, taken only once per night as needed if a middle-of-the-night awakening is followed by difficulty returning to sleep. The recommended doses for women and men are different because women clear zolpidem from the body at a lower rate than men.

2.3 Use with CNS

Depressants The recommended zolpidem tartrate sublingual tablets dose for men and women who are taking concomitant CNS depressants is 1.75 mg. Dose adjustment of concomitant CNS depressants may be necessary when co-administered with zolpidem tartrate sublingual tablets because of potentially additive effects. The use of zolpidem tartrate sublingual tablets with other sedative-hypnotics (including other zolpidem products) at bedtime or the middle of the night is not recommended.

2.4 Use in Geriatric

Patients Geriatric patients may be especially sensitive to the effects of zolpidem. The recommended dose of zolpidem tartrate sublingual tablets in men and women over 65 years old is 1.75 mg, taken only once per night if needed.

2.5 Use in Patients with

Hepatic Impairment The recommended dose of zolpidem tartrate sublingual tablets in patients with hepatic impairment is 1.75 mg, taken only once per night if needed.