Lurasidoneinteractions
lurasidone hydrochloride 80 MG Oral Tablet
This is the interactions section of this product’s FDA label — what the manufacturer documented for this drug. It is not a check of your medication list, and a drug missing from it has not been cleared: licensed clinical databases list far more interactions than any single label does. Before combining medicines, ask a pharmacist, who can check everything you take at once and will do it for free.
Named on this label
- clarithromycin
- carbamazepine
- erythromycin
- ketoconazole
- voriconazole
- fluconazole
- atazanavir
- etravirine
- diltiazem
- efavirenz
- modafinil
- phenytoin
- ritonavir
- verapamil
- rifampin
- lithium
Every name above is printed in the text below. This is not the full set of drugs that interact with this one — it is the set this manufacturer wrote down.
Drug interactions
7.1 Drugs Having
Clinically Important Interactions with Lurasidone Table 34: Clinically Important Drug Interactions with Lurasidone Strong CYP3A4 Inhibitors Clinical Impact: Concomitant use of lurasidone hydrochloride tablets with strong CYP3A4 inhibitors increased the exposure of lurasidone compared to the use of lurasidone hydrochloride tablets alone.
Intervention: Lurasidone hydrochloride tablets should not be used concomitantly with strong CYP3A4 inhibitors.
Examples: Ketoconazole, clarithromycin, ritonavir, voriconazole, mibefradil Moderate CYP3A4 Inhibitors Clinical Impact: Concomitant use of lurasidone hydrochloride tablets with moderate CYP3A4 inhibitors increased the exposure of lurasidone compared to the use of lurasidone hydrochloride tablets alone.
Intervention: Lurasidone hydrochloride tablets dose should be reduced to half of the original level when used concomitantly with moderate inhibitors of CYP3A4.
Examples: Diltiazem, atazanavir, erythromycin, fluconazole, verapamil Strong CYP3A4 Inducers Clinical Impact: Concomitant use of lurasidone hydrochloride tablets with strong CYP3A4 inducers decreased the exposure of lurasidone compared to the use of lurasidone hydrochloride tablets alone.
Intervention: Lurasidone hydrochloride tablets should not be used concomitantly with strong CYP3A4 inducers.
Examples: Rifampin, avasimibe, St. John's wort, phenytoin, carbamazepine Moderate CYP3A4 Inducers Clinical Impact: Concomitant use of lurasidone hydrochloride tablets with moderate CYP3A4 inducers decreased the exposure of lurasidone compared to the use of lurasidone hydrochloride tablets alone.
Intervention: Lurasidone hydrochloride tablets dose should be increased when used concomitantly with moderate inducers of CYP3A4.
Examples: Bosentan, efavirenz, etravirine, modafinil, nafcillin
7.2 Drugs Having
No Clinically Important Interactions with Lurasidone Based on pharmacokinetic studies, no dosage adjustment of lurasidone hydrochloride is required when administered concomitantly with lithium, valproate, or substrates of P-gp or CYP3A4.
Text above is quoted in full from the FDA-approved drug label published by openFDA, effective July 14, 2026. Matched to this product by RxNorm code. Cross-references to other sections of the full prescribing information have been removed, since they point to a document not shown here. Nothing else is changed: no sentence is shortened, reworded or summarised.
This page reproduces regulatory text for reference. It is not medical advice, and KenyRx is not a pharmacy or a prescriber. Talk to a doctor or pharmacist about whether a medicine is right for you.
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