Insulindosage

Only administer subcutaneously (in abdominal wall, thigh, upper arm, or buttocks). Rotate injection sites to reduce risk of lipodystrophy and localized cutaneous amyloidosis. Individualize and adjust dosage based on metabolic needs, blood glucose monitoring results and glycemic control goal. See Full Prescribing Information for dosage adjustments due to drug interactions and patients with renal and hepatic impairment. Administer approximately 30-45 minutes before a meal.

2.1 Important

Administration Instructions Inspect HUMULIN 70/30 visually before use. It should not contain particulate matter and should appear uniformly cloudy after mixing. Do not use HUMULIN 70/30 if particulate matter is seen. Administer HUMULIN 70/30 subcutaneously into the abdominal wall, thigh, upper arm, or buttocks. Rotate injection sites within the same region from one injection to the next to reduce the risk of lipodystrophy and localized cutaneous amyloidosis. Do not inject into areas of lipodystrophy or localized cutaneous amyloidosis. The HUMULIN 70/30 KwikPen dials in 1 unit increments. Use HUMULIN 70/30 KwikPen with caution in patients with visual impairment that may rely on audible clicks to dial their dose. Do not administer HUMULIN 70/30 intravenously and do not use in an insulin infusion pump. Do not mix HUMULIN 70/30 with any other insulins or diluents.

2.2 Dosage Information

Inject HUMULIN 70/30 subcutaneously approximately 30-45 minutes before a meal. The proportion of rapid acting and long acting insulin is fixed in a premixed insulin such as HUMULIN 70/30. Independent adjustment of the basal or prandial dose is not possible when using a premixed insulin. Individualize and adjust the dosage of HUMULIN 70/30 based on the individual's metabolic needs, blood glucose monitoring results and glycemic control goal. Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), changes in renal or hepatic function or during acute illness. During changes to a patient's insulin regimen, increase the frequency of blood glucose monitoring. HUMULIN 70/30 dose requirements may change with changes in level of physical activity, meal patterns (i.e., macronutrient content or timing of food intake), during major illness, or with some coadministered drugs.