Estradioldosage

Exclude pregnancy and discontinue hormonal contraceptives prior to MYFEMBREE initiation. Take one tablet orally once daily. Take the missed dose of MYFEMBREE as soon as possible the same day and then resume regular dosing the next day at the usual time. If concomitant use of oral P-gp inhibitors is unavoidable, take MYFEMBREE at least 6 hours before taking the P-gp inhibitor

2.1 Prior to

Initiation of MYFEMBREE Exclude pregnancy. Discontinue hormonal contraceptives.

2.2 Recommended

Dosage Take one tablet of MYFEMBREE orally once daily at approximately the same time, with or without food. Start MYFEMBREE as early as possible after the onset of menses but no later than seven days after menses has started. The recommended total duration of treatment with MYFEMBREE is 24 months.

2.3 Missed Dose

Take the missed dose of MYFEMBREE as soon as possible the same day and then resume regular dosing the next day at the usual time.

2.4 Dosage Modification for

Concomitant Use with P-gp Inhibitors Avoid concomitant use of MYFEMBREE with oral P-gp inhibitors. If concomitant use is unavoidable, take MYFEMBREE first and separate dosing by at least 6 hours.