Droxidopadosage

Starting dose is 100 mg three times during the day

Titrate by 100 mg three times daily, up to a maximum dose of 600 mg three times daily

Take consistently with or without food

To reduce the potential for supine hypertension, elevate the head of the bed and give the last dose at least 3 hours prior to bedtime

Take droxidopa capsule whole

2.1 Dosing Information

The recommended starting dose of droxidopa capsules is 100 mg, taken orally three times daily: upon arising in the morning, at midday, and in the late afternoon at least 3 hours prior to bedtime (to reduce the potential for supine hypertension during sleep). Administer droxidopa capsules consistently, either with food or without food. Take droxidopa capsule whole. Titrate to symptomatic response, in increments of 100 mg three times daily every 24 to 48 hours up to a maximum dose of 600 mg three times daily (i.e., a maximum total daily dose of 1,800 mg). Monitor supine blood pressure prior to initiating droxidopa capsules and after increasing the dose. Patients who miss a dose of droxidopa capsules should take their next scheduled dose.