Donepezildosage

Mild to Moderate Alzheimer’s Disease: 5 mg to 10 mg once daily Moderate to Severe Alzheimer’s Disease: 10 mg to 23 mg once daily

2.1 Dosing in

Mild to Moderate Alzheimer’s Disease The recommended starting dosage of ARICEPT is 5 mg administered once per day in the evening, just prior to retiring. The maximum recommended dosage of ARICEPT in patients with mild to moderate Alzheimer’s disease is 10 mg per day. A dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks.

2.2 Dosing in

Moderate to Severe Alzheimer’s Disease The recommended starting dosage of ARICEPT is 5 mg administered once per day in the evening, just prior to retiring. The maximum recommended dosage of ARICEPT in patients with moderate to severe Alzheimer’s disease is 23 mg per day. A dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks. A dose of 23 mg per day should not be administered until patients have been on a daily dose of 10 mg for at least 3 months.

2.3 Administration

Information ARICEPT should be taken in the evening, just prior to retiring. ARICEPT can be taken with or without food. The ARICEPT 23 mg tablet should not be split, crushed, or chewed. Allow ARICEPT ODT to dissolve on the tongue and follow with water.