Colesevelamdosage

Obtain lipid parameters, including serum triglyceride (TG) levels, before starting colesevelam hydrochloride for oral suspension.

The recommended dosage for adults and for boys and postmenarchal girls aged 10 to 17 years with primary hyperlipidemia is 3.75 grams daily or one 1.875 grams packet twice daily. The recommended dosage for adults with type 2 diabetes mellitus is 3.75 grams daily or one 1.875 grams packet twice daily. Colesevelam hydrochloride for oral suspension should be taken as follows: For Oral Suspension Take one 3.75 grams packet once daily or one 1.875 grams packet twice daily with a meal. To prepare, empty the entire contents of one packet into the glass or cup. Add ½ cup to 1 cup of water, fruit juice, or diet soft drinks. Stir well and drink.

2.1 Testing

Prior to Initiation of Colesevelam Hydrochloride for Oral Suspension Obtain lipid parameters, including triglyceride (TG) levels, before starting colesevelam hydrochloride for oral suspension. Colesevelam hydrochloride for oral suspension is contraindicated in patients with TG levels >500 mg/dL.

2.2 Recommended

Dosage in Primary Hyperlipidemia and Type 2 Diabetes Mellitus The recommended dosage of colesevelam hydrochloride for oral suspension for adults and for boys and postmenarchal girls aged 10 to 17 years with primary hyperlipidemia is 3.75 grams daily or one 1.875 grams packet twice daily. The recommended dosage of colesevelam hydrochloride for oral suspension for adults with type 2 diabetes mellitus is 3.75 grams daily or one 1.875 grams packet twice daily. Colesevelam hydrochloride for oral suspension should be taken as follows: For Oral Suspension 1.875 gm – Take one packet twice daily 3.75 gm - Take one packet once daily.

2.3 Important

Dosing Information for Primary Hyperlipidemia Colesevelam hydrochloride for oral suspension can be dosed at the same time as a statin, or colesevelam hydrochloride for oral suspension and the statin can be dosed apart. Monitor lipid levels within 4 to 6 weeks after initiation of colesevelam hydrochloride for oral suspension.

2.4 Administration

Instructions For Oral Suspension To prepare, empty the entire contents of one packet into a glass or cup. Add ½ to 1 cup (4 to 8 ounces) of water, fruit juice, or diet soft drinks. Stir well and drink. Take colesevelam hydrochloride for oral suspension with meals. Do not take colesevelam hydrochloride for oral suspension in its dry form. Due to tablet size, colesevelam hydrochloride for oral suspension is recommended for use in the pediatric population.