Cefaclordosage

The absorption of cefaclor extended-release tablets is enhanced when it is administered with food. (See CLINICAL PHARMACOLOGY.) Therefore, cefaclor extended-release tablets should be administered with meals (i.e., at least within one hour of eating). The extended-release tablets should not be cut, crushed, or chewed. See INDICATIONS AND USAGE for information about patients for whom cefaclor extended-release tablets are indicated.

NOTE: 500 mg BID of cefaclor extended-release tablets is clinically equivalent to 250 mg TID of cefaclor immediate-release as a capsule in those indications listed in the INDICATIONS AND USAGE section of this label. 500 mg BID of cefaclor extended-release tablets is NOT equivalent to 500 mg TID of other cefaclor formulations. Adults (age 16 years and older): Type of Infection (as qualified in the INDICATIONS AND USAGE section of this labeling) Total Daily Dose Dose and Frequency Duration Acute Bacterial Exacerbations of Chronic Bronchitis due to H. influenzae (non-ß-lactamase-producing strains only). Moraxella catarrhalis (including ß-lactamase-producing strains), or Streptococcus pneumoniae (See INDICATIONS AND USAGE.) 1000 mg 500 mg q 12 hours 7 days Pharyngitis and/or tonsillitis due to S. pyogenes 750 mg 375 mg q 12 hours 10 days Uncomplicated Skin and Skin Structure Infections due to S. aureus (methicillin-susceptible strains) (See INDICATIONS AND USAGE.) 750 mg 375 mg q 12 hours 7 to 10 days Elderly patients with normal renal function do not require dosage adjustments.