Amlodipinedosage
amlodipine 5 MG / hydrochlorothiazide 25 MG / valsartan 160 MG Oral Tablet [Exforge HCT]
Dosage and administration
Dose once-daily. Titrate up to a maximum dose of 10/320/25 mg. Exforge HCT may be used as add-on/switch therapy for patients not adequately controlled on any two of the following antihypertensive classes: calcium channel blockers, angiotensin receptor blockers, and diuretics. Exforge HCT may be substituted for its individually titrated components.
2.1 General
Considerations Dose once-daily. The dosage may be increased after 2 weeks of therapy. The full blood pressure lowering effect was achieved 2 weeks after being on the maximal dose of Exforge HCT. The maximum recommended dose of Exforge HCT is 10/320/25 mg.
2.2 Add-on/Switch
Therapy Exforge HCT may be used for patients not adequately controlled on any 2 of the following antihypertensive classes: calcium channel blockers, angiotensin receptor blockers, and diuretics. A patient who experiences dose-limiting adverse reactions to an individual component while on any dual combination of the components of Exforge HCT may be switched to Exforge HCT containing a lower dose of that component to achieve similar blood pressure reductions.
2.3 Replacement
Therapy Exforge HCT may be substituted for the individually titrated components.
2.4 Use With
Other Antihypertensive Drugs Exforge HCT may be administered with other antihypertensive agents.
Text above is quoted in full from the FDA-approved drug label published by openFDA, effective December 12, 2025. Matched to this product by RxNorm code. Cross-references to other sections of the full prescribing information have been removed, since they point to a document not shown here. Nothing else is changed: no sentence is shortened, reworded or summarised.
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